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Osteoarthritis is a disease of the joints. Unlike many other forms of arthritis, such as rheumatoid arthritis and systemic lupus, osteoarthritis does not affect other organs of the body.


Joint pain is usually worse later in the day. There can be swelling, warmth, and creaking of the affected joints. Pain and stiffness of the joints can also occur after long periods of inactivity, for example, sitting in a theater.

In severe osteoarthritis, complete loss of cartilage causes friction between bones, causing pain at rest or pain with limited motion.

Osteoarthritis is caused by aging joints, injury, and obesity. 


PENNSAID 2%: Osteoarthritis (OA) can cause the pain you feel in your knee.PENNSAID 2% is targeted pain relief that from a topical, nonsteroidal anti-inflammatory drug, that you apply directly to your knee. It is also called NSAID for short.

VIMOVO delivers what naproxen 500 mg alone can not—less risk of developing stomach ulcers

VIMOVO delivers relief from OA/RA pain and inflammation with at least 70% lower risk of developing stomach ulcers than patients on naproxen alone

Naproxen relieves signs and symptoms of:
Osteoarthritis (OA), rheumatoid arthritis (RA), and ankylosing spondylitis (AS) in adults
Juvenile idiopathic arthritis (JIA) in adolescents*
Esomeprazole Magnesium decreases the risk of developing stomach ulcers from naproxen

DUEXIS delivers what ibuprofen 800 mg alone can not—less risk of developing stomach ulcers

In 2 studies of people who required NSAID treatment for chronic pain conditions such as osteoarthritis and rheumatoid arthritis, treatment with DUEXIS reduced the risk of developing stomach ulcers by about 50% compared with people in the studies who took ibuprofen without any gastroprotective medicine.

If you have osteoarthritis or rheumatoid arthritis, chronic NSAID use can put you at risk.

1 in 4 people taking NSAIDs regularly, like ibuprofen, will develop a stomach ulcer

Stomach ulcers can occur in under 1 week

Most people will never even feel the stomach ulcer developing—but stomach ulcers can be very dangerous and lead to serious health complications

Experts recommend taking a medicine that can protect the stomach (gastroprotective), along with NSAIDs, as one way to decrease the possibility of getting stomach ulcers in certain patients

TYMLOS is indicated for the treatment of postmenopausal women with osteoporosis at high risk for fracture defined as a history of osteoporotic fracture, multiple risk factors for fracture, or patients who have failed or are intolerant to other available osteoporosis therapy.


RECLAST (ZOLEDRONIC ACID) is indicated for the treatment of osteoporosis in postmenopausal women. Zoledronic Acid reduces the incidence of fractures. Zoledronic Acid is used to increase bone mass in men with osteoporosis. It works by decreasing the activity of the cells in bone that cause resorption and recycling of the bone.

More Information

Treatment depends on the affected joint, including the hand, wrist, neck, back, knee, and hip, and involves medication and exercise. If you are overweight, weight loss may improve osteoarthritis symptoms.

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