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Gout is a form of inflammatory arthritis that develops in some people who have high levels of uric acid in the blood. The acid can form needle-like crystals in a joint and cause sudden, severe episodes of pain, tenderness, redness, warmth, and swelling.

Gout is the most common form of inflammatory arthritis, affecting 9.2 million Americans.* Like other types of arthritis, gout is an ongoing disease that can get worse without the right treatment.

You probably know that your gout is caused by too much uric acid in your system. High levels of uric acid can build up and form crystals in your joints and throughout your body. As the crystals accumulate, they can form clumps called tophi that may damage the bone. At this point, patients can find it difficult to move without experiencing pain.


KRYSTEXXA works differently to treat gout. Most gout medications target uric acid levels by affecting the production or removal of uric acid from the body.


KRYSTEXXA changes uric acid to a substance your body can easily get rid of through urine:

  • KRYSTEXXA rapidly lowers uric acid levels. Within 24 hours the average uric acid level of patients receiving KRYSTEXXA was 1 mg/dL

  • By lowering uric acid levels, KRYSTEXXA helps dissolve the buildup of uric acid crystals from your body

  • KRYSTEXXA is not recommended if you have high levels of uric acid without a history of gout.

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